Celebrating the 100th Anniversary of virology, Tobacco Mosaic Virus: One Hundred Years of Contributions to Virology is an anthology of this past century's classic papers written about tobacco mosaic virus and its impact in the field of virology and related studies. A historical perspective shows an appreciation for this important virus and how these classic experiments have led to our current understanding of all types of viruses today.

Tobacco Mosaic Virus: One Hundred Years of Contributions to Virology

Introduction

On Beijerinck’s Concept of a Contagium Vivum Fluidum. Milton Zaitlin

Anon. 1898. Prof. Beijerinck, on a contagium vivum fluidum, causing the spot-disease of tobacco leaves. Nature 59:216.

Beijerinck, M. W. 1898. Concerning a contagium vivum fluidum as cause of the spot disease of tobacco leaves. In: “Phytopathological Classics, No. 7” (J. Johnson, ed.). American Phytopathological Society, pp. 33-52.

H. H. McKinney and Cross Protection, Robert W. Fulton

McKinney, H. H. 1929. Mosaic diseases in the Canary Islands, West Africa, and Gibraltar. Journal of Agricultural Research 39:557-578.

Francis O. Holmes and the Local Lesion Assay, John G. Shaw

Holmes, F. O. 1929. Local lesions in tobacco mosaic. Botanical Gazette 87:39-55.

The Chemical Nature of Tobacco Mosaic Virus Particles, Bryan D. Harrison

Stanley, W. M. 1935. Isolation of crystalline protein processing the properties of tobacco-mosaic virus. Science 81:644-645.

Bawden, F. C., Pirie, N. W., Bernal, J. D., and Fankuchen, I. 1936. Liquid crystalline substances from virus-infected plants. Nature 138:1051-1052.

Commentary on Bernal and Fankuchen. Gerald Stubbs

Bernal, J. D., and Fankuchen, I. 1937. Structure types of protein ‘crystals’ from virus-infected plants. Nature 139:923-924.

Bernal, J. D., and Fankuchen, I. 1941. X-ray and crystallographic studies of plant virus preparations. III. Journal of General Physiology 25:147-165.

The Electron Microscopy of Tobacco Mosaic Virus. Robert W. Horne

Kausche, G. A., Pfankuch, E., and Ruska, H. 1939. Die Sichtbarmachung von pflanzlichem Virus im Übermikroskop. Naturwissenschaften 27:292-299.

Commentary on the Two Papers by Caspar and Franklin. Aaron Klug

Caspar, D. L. D. 1956. Radial density distribution in the tobacco mosaic virus particle. Nature 177:928.

Franklin, R. E. 1956. Location of the ribonucleic acid in the tobacco mosaic virus particle. Nature 177:928-930.

UV Irradiation of Tobacco Mosaic Virus. Albert Siegel

Siegel, A., and Wildman, S. G. 1956. The inactivation of the infectious centers of tobacco mosaic virus by ultraviolet light. Virology 2:69-82.

In Vitro Assembly of Tobacco Mosaic Virus, George Lomonossoff

Fraenkel-Conrat, H., and Williams, R. C. 1955. Reconstitution of active tobacco mosaic virus from its inactive protein and nucleic acid components. Proceedings of the National Academy of Sciences (USA) 41:690-698.

TMV in Tübingen (1945-1965). K.-W. Mundry

Gierer, A., and Schramm, G. 1956. Infectivity of ribonucleic acid from tobacco mosic virus. Nature 177:702-703.

Gierer, A., and Mundry, K.-W. 1958. Production of mutants of tobacco mosaic virus by chemical alteration of its ribonucleic acid in vitro. Nature 182:1457-1458.

Wittmann, H. G. 1960. Comparison of the tryptic peptides of chemically induced and spontaneous mutants of tobacco mosaic virus. Virology 12:609-612.

Comments on Takebe and Otsuki. Milton Zaitlin

Takebe, I., and Otsuki, Y. 1969. Infection of tobacco mesophyll protoplasts by tobacco mosaic virus. Proceedings of the National Academy of Sciences (USA) 64:843-848.

Identification of the TMV Coat Protein Messenger RNA. Andrew O. Jackson

Hunter, T. R., Hunt, T., Knowland, J., and Zimmern, D. 1976. Messenger RNA for the coat protein of tobacco mosaic virus. Nature 260:759-764.

The Tale of the Two-Tailed Monsters. Ken Richards

Lebeurier, G., Nicolaieff, A., and Richards, K. E. 1977. Inside-out model of self-assembly of tobacco mosaic virus. Proceedings of the National Academy of Sciences (USA) 74:149-153.

Butler, P. J. G., Finch, J. T., and Zimmern, D. 1977. Configuration of tobacco mosaic virus RNA during virus assembly. Nature 265:217-219.

Transport of Tobacco Mosaic Virus From Cell-to-Cell. Masamichi Nishiguchi and Fusao Motoyoshi

Nishiguchi, M., Motoyoshi, F., and Oshima, N. 1978. Behaviour of a temperature sensitive strain of tobacco mosaic virus in tomato leaves and protoplasts. Journal of General Virology 39:53-61.

Cotranslational Disassembly of Tobaco Mosaic Virus. T. Michael A. Wilson

Wilson, T. M. A. 1984. Cotranslational disassembly of tobacco mosaic virus in vitro. Virology 137:255-265.

Avoiding the Triple Flip and Two Twists in Cloning TMV. William O. Dawson

Goelet, P., Lomonossoff, G. P., Butler, P. J., Akam, M. E., Gait, M. J., and Karn, J. 1982. Nucleotide sequence of tobacco mosaic virus RNA. Proceedings of the National Academy of Sciences (USA) 79:5818-5822.

Dawson, W. O., Beck, D. L., Knorr, D. A., and Grantham, G. L. 1986. cDNA cloning of the complete genome of tobacco mosaic virus and production of infectious transcripts. Proceedings of the National Academy of Sciences (USA) 83:1831-1836.

Coat Protein Mediated Resistance, Roger N. Beachy

Abel, P. P., Nelson, R. S., De, B., Hoffmann, N., Rogers, S. G., Fraley, R. T., and Beachy, R. N. 1986. Delay of disease development in transgenic plants that express the tobacco mosaic virus coat protein gene. Science 232:738-743.

The 54 kDa Protein Encoded by Tobacco Mosaic Virus and Replicase-Mediated Resistance. Milton Zaitlin

Golemboski, D. B., Lomonossoff, G. P., and Zaitlin, M. 1990. Plants transformed with a tobacco mosaic virus nonstructural gene sequence are resistant to the virus. Proceedings of the National Academy of Sciences (USA) 87:6311-6315.

Acknowledgments